Patient JS (age 53) has chronic cavitary pulmonary aspergillosis and failed itraconazole therapy. After taking voriconazole for several months she relatively suddenly developed florid conjunctivitis which is attributable to voriconazole. This occurred without facial erythema, which is unusual. Voriconazole has been continued.
Image 1. The chest x-ray shows extensive bilateral nodular disease, most consistent with a fungal infection, or possibly tuberculosis. He was treated with a bucket face mask with 80% oxygen and voriconazole.
A Colonies on MEA +20 % sucrose after 2 weeks; B ascomata, x 40; C conidiophore of Aspergillus glaucus x 920;D conidiophore of Aspergillus glaucus x920 E. portion of ascoma with asci x 920. F ascospores x2330.
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