IPA in leukaemia (A)

Date: 26 November 2013

  • Image A. Pt TH 05/02/90

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5/2/90 Before itraconazole therapy

Copyright: n/a

Notes:

Bilateral diffuse invasive pulmonary aspergillosis, proven by transbronchial biopsy after resolution of neutropenia. He was treated with oral itraconazole 400mg daily with a good outcome. His case was reported in Denning DW, Lee JY, Hostetler JS, Pappas P, Kauffman CA, Dewsnup DH, Galgiani JN, Graybill JR, Sugar AM, Catanzaro A, Gallis H, Perfect JR, Dockery B, Dismukes WE, Stevens DA, NIAID Mycoses Study Group multicenter trial of oral itraconazole therapy of invasive aspergillosis. Am J Med 1994; 97: 135-144.

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  • Title

    Legend

  • Aspergillus persii

    Culture plates on different media. A Colonies on CZ at 24oC, B on CYA at 20oC C on SAB at 37oC, D on CYA at 24oC

    persiicolonies

  • Sinusitis radiology

    D Sinusitis radiology with fluid level

  • Bronchiectasis

    C Bronchiectasis white cell scan (right) – left shows a normal scan for comparison

  • Bronchiectasis

    B Bronchogram showing bronchiectasis

  • Saccular bronchiectasis

    A Bronchogram showing saccular bronchiectasis

  • Mucous containing Charcot-Leyden crystals

    Mucous containing Charcot-Leyden crystals, stained with H & EA 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material re

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  • Echinocandin B 3d

  • D-0870

  • Cilofungin 3d