Date: 26 November 2013
Aspergillus terreus Thom. Conidial head of Aspergillus terreus. Conidial heads are compact, columnar and biseriate. Conidiophores are hyaline to slightly yellow and smooth walled.
Copyright:
With thanks to G Kaminski. D Ellis and R Hermanis Mycology Unit, Women’s & Children’s Hospital , Adelaide, South Australia 5006
Notes:
Colonies on CYA 40-50 mm diam, plane, low and velutinous, usually quite dense; mycelium white; conidial production heavy, brown (Dark Blonde to Camel, 5-6D4); reverse pale to dull brown or yellow brown. Colonies on MEA 40-60 mm diam, similar to those on CYA or less dense. Colonies on G25N 18-22 mm diam, plane or irregularly wrinkled, low and sparse; conidial production light, pale brown; brown soluble pigment sometimes produced; reverse brown. No growth at 5°C. Colonies at 37°C growing very rapidly, 50 mm or more diam, of similar appearance to those on CYA at 25°C.Conidiophores borne from surface hyphae, stipes 100-250 μm long, smooth walled; vesicles 15-20 μm diam, fertile over the upper hemisphere, with densely packed, short, narrow metulae and phialides, both 5-8 μm long; conidia spherical, very small, 1.8-2.5 μm diam, smooth walled, at maturity borne in long, well defined columns.Distinctive featuresVelutinous colonies formed at both 25°C and 37°C, uniformly brown, with no other colouration, and minute conidia borne in long columns make Aspergillus terreus a distinctive species.
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Drug rashes: Drug interactions between steroids and anti-fungal drugs – (ecchymosis)
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Reference: Muco-cutaneous retinoid effects and facial erythema related to the novel triazole antifungal agent voriconazole. Denning, DW & Griffiths, CEM. Clin.Exp Dermatol 2001, 26(8), 648-53.
Courtesy of Dr D Denning, Wythenshawe Hospital, Manchester.(© Fungal Research Trust), ,
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Micrographs of A. niger conidia & conidial heads provided by Amaliya Stepanova, Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. terreus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Micrographs of A. fumigatus conidia & conidial heads provided by Amaliya Stepanova, , Head of Laboratory pathomorphology and cytology at Kashkin Research Institute, Russian Federation.
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Patients has history of ABPA complicating long standing asthma. His total IgE has fluctuated between 2,200 and 4,600 KU/L, his Aspergillus IgE between 36.3 and 65.4 kAU/L and Aspergillus IgG from 87-154 mg/L. He has been taking long term itraconazole.
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