Description:
Candida albicans is one of the fungal species most commonly causing life threatening infections in vulnerable patients. Our group is studying the mitochondria in Candida albicans cells.
Just like in our cells the mitochondria are the batteries of the cell, producing energy required for growth and in fungal cells can also influence infection.
The mitochondria can influence components of the fungal cell wall and its ability to infect us.
If we understand how mitochondria are influencing these factors, we can develop new anti-fungals or we can use existing anti-fungals in new combinations in order to tackle life threatening infections.
Lucian Duvenage works in Dr Campbell Gourlay’s lab at the University of Kent
Medical and Patient education videos
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Title
Description
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane. Watch this animation for more information.
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Fungi are eukaryotic organisms and are not related to bacteria. As eukaryotes, they contain membrane bound organelles and possess a cell membrane surrounded by a rigid cell wall. Watch this animation for more information on the unique structural properties of fungi.
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A review of antifungals, focusing on amphotericin B, azoles, and echinocandins. Structure, mechanism, spectrum of antifungal activity, common clinical uses, and common side effects/toxicities are all discussed. (April 2015)
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane.
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane.
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Healthy Buildings 2015 Europe – Eindhoven, The Netherlands
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Healthy Buildings 2015 Europe – Eindhoven, The Netherlands
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Healthy Buildings 2015 Europe – Eindhoven, The Netherlands
