Ergosta-7,22-diene-3β,5α,6β-triol

Trivial name:

5α-​Ergosta-​7,​22-​diene-​3β,​5,​6-​triol (7CI); 5α-​Ergosta-​7,​22-​diene-​3β,​5,​6β-​triol (6CI,​8CI); (22E)​-​Ergosta-​7,​22-​diene-​3β,​5α,​6β-​triol; (22E,​24R)​-​Ergosta-​7,​22-​dien-​3β,​5α,​6β-​triol; (22E,​24R)​-​Ergosta-​7,​22-​diene-​3β,​5α,​6β-​triol; (3β,​5α,​6β,​22E)​-​Ergosta-​7,​22-​diene-​3,​5,​6-​triol; Cerevisterin; Cerevisterol; Ergosta-​7,​22-​diene-​3β,​5α,​6β-​triol

Systematic name:

Ergosta-​7,​22-​diene-​3,​5,​6-​triol, (3β,​5α,​6β,​22E)​-

Molecular formulae: 

C28 H46 O3

Molecular weight: 430.66

Chemical abstract number: 516-37-0

Literature reference:

  • Studies on the constituents from mycelia of Aspergillus awamori nakazawa. Zhang, Wei; Wang, Tao; Pei, Yuehu; Chi, Jifei. Zhongguo Yaowu Huaxue Zazhi (2001), 11(6), 340-342.
    Sterols from Aspergillus ochraceus 43. Li, Guoyou; Li, Bogang; Liu, Guangye; Zhang, Guolin. Yingyong Yu Huanjing Shengwu Xuebao (2005), 11(1), 67-70.
    Two new metabolites with cytotoxicities from deep-​sea fungus, Aspergillus sydowi YH11-​2. Li, De-Hai; Cai, Sheng-Xin; Tian, Li; Lin, Zhen-Jian; Zhu, Tian-Jiao; Fang, Yu-Chun; Liu, Pei-Pei; Gu, Qian-Qun; Zhu, Wei-Ming. Archives of Pharmacal Research (2007), 30(9), 1051-1054.
    Secondary metabolites from an algicolous Aspergillus versicolor strain. Miao, F. P., X. D. Li, et al. (2012). Marine drugs 10(1): 131-139
    Phosphopantetheinyl transferase CfwA​/NpgA is required for Aspergillus nidulans secondary metabolism and asexual development. Marquez-Fernandez, Olivia; Trigos, Angel; Ramos-Balderas, Jose Luis; Viniegra-Gonzalez, Gustavo; Deising, Holger B.; Aguirre, Jesus. Eukaryotic Cell (2007), 6(4), 710-720.
    Ergosterimide, a new natural Diels-​Alder adduct of a steroid and maleimide in the fungus Aspergillus niger. Zhang, Yi; Li, Xiao-Ming; Proksch, Peter; Wang, Bin-Gui. Steroids (2007), 72(9-10), 723-727.
    Asporyergosterol, a new steroid from an algicolous isolate of Aspergillus oryzae. Qiao, Ming-Feng; Ji, Nai-Yun; Liu, Xiang-Hong; Li, Fang; Xue, Qin-Zhao. Natural Product Communications (2010), 5(10), 1575-1578.
    Antimicrobial ergosteroids and pyrrole derivatives from halotolerant Aspergillus flocculosus PT05-​1 cultured in a hypersaline medium. Zheng, Jinkai; Wang, Yi; Wang, Junfeng; Liu, Peipei; Li, Jing; Zhu, Weiming. Extremophiles (2013), 17(6), 963-971

References URL: 

Aspergillus Species known to produce this metabolite:

Structure image:  

Mycotoxin & Metabolites

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