Austin

ID 2: 149

Toxin: y

Systematic name:

Spiro[1H-6,11b-methano-4H-furo[3,4-e][3]benzoxocin-9(10H),3′(6’H)-[2H]pyran]-1,4,6′-trione, 7-(acetyloxy)-3,3a,6,7,11,11a-hexahydro-3a-hydroxy-2′,2′,3,6,8,11a-hexamethyl-12-methylene-, (3S,3’S,3aS,6R,7R,11aS,11bS)-

Molecular formulae: 

C27H32O9

 

Molecular weight: 500.5

Chemical abstract number: 61103-89-7

Chemical type: Dihydro-α-pyrone

Literature reference:

  • Austin, a novel polyisoprenoid mycotoxin from Aspergillus ustus. Chexal, K. K.; Springer, James P.; Clardy, Jon; Cole, Richard J.; Kirksey, Jerry W.; Dorner, Joe W.; Cutler, Horace G.; Strawter, Billy J. Journal of the American Chemical Society (1976), 98(21), 6748-50.
    Studies on fungal metabolites. Part 3. Carbon-​13 NMR spectral and structural studies on austin and new related meroterpenoids from Aspergillus ustus, Aspergillus variecolor, and Penicillium diversum. Simpson, Thomas J.; Stenzel, Desmond J.; Bartlett, Alan J.; O’Brien, Eugene; Holker, John S. E. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1982), (11), 2687-92.

References URL: 

Aspergillus Species known to produce this metabolite:

Toxicity:

Oral LD50 250 to 375 mg/kg body-weight in day-old cockerels. Insecticide.

Structure image:  

Austinweb

Date uploaded: 2010-08-25 14:24:48

Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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