Aspochalasin K

Toxin: y

Systematic name:

1H-​Cycloundec[d]​isoindole-​1,​15(2H)​-​dione, 3,​3a,​4,​6a,​9,​10,​11,​12,​13,​14-​decahydro-​11,​13-​dihydroxy-​12-​methoxy-​4,​5,​8-​trimethyl-​3-​(2-​methylpropyl)​-​, (3S,​3aR,​4S,​6aS,​7E,​15aS)​-

Molecular formulae: 

C₂₅H₃₉NO₅

 

Molecular weight: 433.6

Chemical abstract number: 670225-71-5

Literature reference:

• Aspochalasins I, J, and K: three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran desert. Zhou, Guang-Xiong; Wijeratne, E. M. Kithsiri; Bigelow, Donna; Pierson, Leland S., III; VanEtten, Hans D.; Gunatilaka, A. A. Leslie. Journal of Natural Products (2004), 67(3), 328-332

References URL: 

• http://pubs.acs.org/doi/abs/10.1021/np030353m?source=chemport&cookieSet=1&cookieSet=1&cookieSet=1&cookieSet=1

Aspergillus Species known to produce this metabolite:

• /species/flavipes

Toxicity:

Weak to moderate cytotoxicity

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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