Aspergillomarasmine A

Trivial name:

Aspartic acid, N-​[2-​[(2-​amino-​2-​carboxyethyl)​amino]​-​2-​carboxyethyl]​-​, L- (7CI,​8CI); L-​Aspartic acid, N-​[2-​[(2-​amino-​2-​carboxyethyl)​amino]​-​2-​carboxyethyl]​-​, [R-​(R*,​R*)​]​-; Aspergillomarasmine A; Toxin C (Pyrenophora teres)

Systematic name:

L-​Aspartic acid, N-​[(2R)​-​2-​[[(2R)​-​2-​amino-​2-​carboxyethyl]​amino]​-​2-​carboxyethyl]​-

Molecular formulae: 

C₁₀ H₁₇ N₃ O₈

 

Molecular weight: 307.3

Chemical abstract number: 3484-65-9

Literature reference:

• Two new natural phytotoxins: aspergillomarasmine A and B and their relation to lycomarasmine and its derivatives. Robert, Malka; Barbier, Michel; Lederer, Edgar; Roux, Louis; Biemann, Klaus; Vetter, Walter. Bulletin de la Societe Chimique de France (1962), 187-8
  Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance. King AM, Reid-Yu SA, Wang W, King DT, De Pascale G, Strynadka NC, Walsh TR, Coombes BK, Wright GD. Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445.

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/compound/197028
• http://www.nature.com/nature/journal/v510/n7506/full/nature13445.html
• https://www.jstage.jst.go.jp/article/bbb1961/47/11/47_11_2693/_article
• http://onlinelibrary.wiley.com/doi/10.1002/hlca.19650480409/abstract
• https://pubchem.ncbi.nlm.nih.gov/compound/Aspergillomarasmine-A

Aspergillus Species known to produce this metabolite:

• /species/a-versicolor
• /species/a-flavus-var-oryzae
• /species/a-oryzae

Toxicity:

Antibiotic enhancer

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

Search Metabolite papers here