3-Nitropropionic acid

ID 2: 445

Toxin: y

Molecular formulae: 

C₃H₅NO₄

Molecular weight: 119.1

Chemical abstract number: 504-88-1

Chemical type: Aliphatic acid

Literature reference:

• The production of β-​nitropropionic acid by a strain of Aspergillus flavus. Bush, Milton T.; Touster, Oscar; Brockman, Jean Early Journal of Biological Chemistry (1951), 188, 685-93.
  An antibiotic substance, oryzacidin, produced by Aspergillus oryzae. V. Existence of β-​nitropropionic acid in the fermentation broth. Nakamura, Seiji; Shimoda, Chuji. From Nippon Nogei Kagaku Kaishi (1954), 28, 909-13

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/compound/1678
• http://www.jbc.org/content/188/2/685.full.pdf+html?sid=6e55e767-8726-48a0-8e3a-6e3ebc52a2a0

Aspergillus Species known to produce this metabolite:

• /species/a-flavus
• /species/a-wentii
• /species/a-oryzae

Toxicity:

LD50 in mice 160 to 240 mg/kg body-weight given in sodium bicarbonate solution. Symptoms include apnea, convulsions, conjestion in subcutaneous vessels and lungs, as well as a mottled liver.

Date uploaded: 2005-12-11 00:00:00

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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