New Antifungal Drugs, New Approaches and Vaccines

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.

1 December 2016

Trans-ungual Delivery of AR-12, a Novel Antifungal Drug.

13 March 2017

ram1 gene, encoding a subunit of farnesyltransferase, contributes to growth, antifungal susceptibility to amphotericin B of Aspergillus fumigatus.

4 February 2017

In vitro antifungal activity of farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida.

5 December 2013

In vitro antifungal activity of farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida.

5 December 2013

Evaluation of the antifungal activity of SCY-078 in combination with other antifungals against Aspergillus strains

27 April 2017

Pharmacodynamics of F901318 against Aspergillus fumigatus in a rabbit model of invasive pulmonary aspergillosis (IPA)

27 April 2017

A prospective, phase 2, multicentre, open-label, randomized, comparative study to estimate the safety, tolerability, pharmacokinetics, and efficacy of oral SCY-078 vsstandard-of-care following initial intravenous echinocandin therapy in the treatment of..

Phase 2

27 April 2017

In-vitro activity of F901318 and comparators against clinical isolates of cryptic species of Aspergillus

27 April 2017

Antifungal peptides: a potential new class of antifungals for treating vulvovaginal candidiasis caused by fluconazole-resistant Candida albicans.

24 April 2017