Gliotoxin G (1)

ID 2: 236

Toxin: n

Trivial name:

2,​3-​Dithia-​5,​7-​diazabicyclo[2.2.2]​octane-​6,​8-​dione, 5,​7-​bis(methoxymethyl)​-​1,​4-​bis(phenylmethyl)​-​, (±)​-

Systematic name:

2,3-Dithia-5,7-diazabicyclo[2.2.2]octane-6,8-dione, 5,7-bis(methoxymethyl)-1,4-bis(phenylmethyl)-

Molecular formulae: 

C₂₂H₂₄N₂O₄S₂

Molecular weight: 444.57

Chemical abstract number: 87869-04-3

Literature reference:

• Structure and synthesis of cis-​3,​6-​dibenzyl-​3,​6-​bis(methylthio)​piperazine-​2,​5-​dione, a new metabolite of Aspergillus terreus. Kirby, Gordon W.; Robins, David J.; Stark, W. Marshall. Journal of the Chemical Society, Chemical Communications (1983), (15), 812-13.
  Partial synthesis of gliotoxin G, an epitetrathiodioxopiperazine. Kirby, Gordon W.; Rao, Ghanakota V.; Robins, David J.; Stark, W. Marshall. Tetrahedron Letters (1986), 27(45), 5539-40.

References URL: 

• http://pubs.rsc.org/en/Content/ArticleLanding/1983/C3/c39830000812#!divAbstract
• http://www.sciencedirect.com/science/article/pii/S0040403900852612

Aspergillus Species known to produce this metabolite:

• /species/a-fumigatus
• /species/a-terreus

Date uploaded: 2008-07-07 16:30:55

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Mycotoxin & Metabolites

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