Secondary metabolites (sometimes referred to as extrolites) are natural products synthesised by fungi, bacteria and plants. They are not directly required for the growth and development of the organism, but their function instead is to provide biological advantages for its survival and reproduction. For instance, the antibiotic penicillin is a secondary metabolite produced by the fungi Penicillium; Alexander Fleming famously identified the substance’s bactericidal effect when he discovered mould contaminating and killing Staphylococcus aureus on petri dishes he had been working on.
These low-weight molecules can display a vast range of biological activities, and often have beneficial applications in industries from pharmaceutics to agriculture. However, a sub-group of fungal secondary metabolites, called mycotoxins, can be very harmful to human and animal health.
Aspergillus species produce a large number of secondary metabolites. We attempt to list them all below and collect any published literature on the subject (see bottom of page).
Aspergillus Metabolites
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Metabolite
Produced by (species)
Molecular weight
References
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399.0
428.5
445.5
443.5
321.5
138.1
264.3
138.1
182.2
Metabolite Papers
Showing 10 posts of 644 posts found.-
Title
Author
Year
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Pena GA, Pereyra CM, Armando MR, Chiacchiera SM, Magnoli CE, Orlando JL, Dalcero AM, Rosa CA, Cavaglieri LR
2010
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Steffan N, Grundmann A, Afiyatullov S, Ruan H, Li SM
2009
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Nielsen KF, Mogensen JM, Johansen M, Larsen TO, Frisvad JC
2009
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López-Gresa MP, Cabedo N, González-Mas MC, Ciavatta ML, Avila C, Primo J
2009
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Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR, Archer D, Bencina M, Braus G, Coutinho P, von Döhren H, Doonan J, Driessen AJ, Durek P, Espeso E, Fekete E, Flipphi M, Estrada CG, Geysens S, Goldman G, de Groot PW, Hansen K, Harris SD, Heinekamp T, Helmstaedt K, Henrissat B, Hofmann G, Homan T, Horio T, Horiuchi H, James S, Jones M, Karaffa L, Karányi Z, Kato M, Keller N, Kelly DE, Kiel JA, Kim JM, van der Klei IJ, Klis FM, Kovalchuk A, Krasevec N, Kubicek CP, Liu B, Maccabe A, Meyer V, Mirabito P, Miskei M, Mos M, Mullins J, Nelson DR, Nielsen J, Oakley BR, Osmani SA, Pakula T, Paszewski A, Paulsen I, Pilsyk S, Pócsi I, Punt PJ, Ram AF, Ren Q, Robellet X, Robson G, Seiboth B, van Solingen P, Specht T, Sun J, Taheri-Talesh N, Takeshita N, Ussery D, vanKuyk PA, Visser H, van de Vondervoort PJ, de Vries RP, Walton J, Xiang X, Xiong Y, Zeng AP, Brandt BW, Cornell MJ, van den Hondel CA, Visser J, Oliver SG, Turner G
2009
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Frisvad JC, Samson RA
2004
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Schroeckh V, Scherlach K, Nützmann HW, Shelest E, Schmidt-Heck W, Schuemann J, Martin K, Hertweck C, Brakhage AA
2009
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Schmidt-Heydt M, Abdel-Hadi A, Magan N, Geisen R
2009
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Zhao K, Ping W, Li Q, Hao S, Zhao L, Gao T, Zhou D
2009