Topic:David Moore's Medical Mycology Blog
Traditional Chinese medicine (TCM) uses many products derived from fungi, including Lentinula edodes (shiitake). Evidence, in the form of published papers, regarding its usefulness has been examined. The review finds that the anti-tumour claims are substantiated, especially those of the lentinan polysaccharide isolated from shiitake. Lentinan is also found to be an immunomodulator, although the medicinal value of these findings are yet to be reliably established. Cholesteremic effects were shown but there was disagreement over the details of the effects. It was concluded that Lentinula edodes does have much potential in medicine but further research is needed.
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