Trivial name: 

2,​3,​5-​Piperazinetrione, 6-​[[2-​(1,​1-​dimethylallyl)​-​6-​(3-​methyl-​2-​butenyl)​indol-​3-​yl]​methylene]​- (8CI); Piperazinetrione, 6-​[[2-​(1,​1-​dimethyl-​2-​propenyl)​-​6-​(3-​methyl-​2-​butenyl)​-​1H-​indol-​3-​yl]​methylene]​-​, (6Z)​- (9CI); Piperazinetrione, [[2-​(1,​1-​dimethyl-​2-​propenyl)​-​6-​(3-​methyl-​2-​butenyl)​-​1H-​indol-​3-​yl]​methylene]​-​, (Z)​-; Alkaloid E 9, from Aspergillus amstelodami; Neoechinulin; Neoechinuline

Systematic name: 

2,​3,​5-​Piperazinetrione, 6-​[[2-​(1,​1-​dimethyl-​2-​propen-​1-​yl)​-​6-​(3-​methyl-​2-​buten-​1-​yl)​-​1H-​indol-​3-​yl]​methylene]​-​, (6Z)​-

Molecular formulae: 


Molecular weight: 


Chem abstract number: 


Literature reference: 

Neoechinuline: a new indole metabolite from Aspergillus amstelodami. Barbetta, Marco; Casnati, Giuseppe; Pochini, A.; Selva, A. Tetrahedron Letters (1969), 51, 4457-60.
 Secondary metabolites from Eurotium species, Aspergillus calidoustus and A. insuetus common in Canadian homes with a review of their chemistry and biological activities. Slack, Gregory J.; Puniani, Eva; Frisvad, Jens C.; Samson, Robert A.; Miller, J. David. Mycological Research (2009), 113(4), 480-490.
 Eurocristatine, a new diketopiperazine dimer from the marine sponge-​associated fungus Eurotium cristatum. Gomes, Nelson M.; Dethoup, Tida; Singburaudom, Narong; Gales, Luis; Silva, Artur M. S.; Kijjoa, Anake. Phytochemistry Letters (2012), 5(4), 717-720.

Chemical type: 


Structure image: 

Species known to produce this metabolite: 

3d image file .s3d (get free desktop viewer at 

jmol file (.mol) requires Java to run ( 

Date uploaded: 

2005-12-13 00:00:00