Nasal Fungal Culture In Allergic Rhinitis And Healthy Children
RATIONALE: Allergy to airborne fungus can cause rhinitis, hence the exposure to spores inside home is an imprtant factor of sensitizaiton. The role of allergy in chronic rhinosinusitis (CRS) is a pertinent yet unresolved issue. The aim of this study was to evaluate the fungus culture of nasal secretions in allergic rhinitis, allergic rhinitis with CRS, and healthy children. METHODS: The study was performed in 100 children (4-15 year-olds) during December 2007 through August 2008. We categorized the children into three groups: children having allergic rhinitis without CRS (Group I, n = 40), allergic rhinitis with CRS (Group 2, n = 40), and healthy children (Group 3, n = 20). Nasal secretion was collected from all children, and the sample was cultured on the agar plates (Bukard Co.), which were incubated at 28Â°C for 48764;6 days. The fungi were identified by morphological method. RESULTS: Positive cultures for fungi were obtained in 26 of 40 (65.0%) CRS patients, and 9 of 20 (45.0%) healthy children. The 6 different organisms were cultured from the nasal secretion and those were Yeast, Alternaria, Cladosporium, Penicillium, Aspergillus, Fusarium. Cladosporium, Aspergillus, Alternaria, and Penicilium were frequently isolated from CRS patients and healthy children. Positive skin test rates and serum eosinophil count were not different between the patients with positive fungus culture and those with negative culture. CONCLUSIONS: The six fungus organisms were cultured from the nasal secretions. The CRS was frequently related with positive fungus culture. Further studies are necessary to evaluate longer follow up of fungus cultures.
Full conference title:
American Academy of Allergy Asthma & Immunology