Citrinin

ID 2: 50

Toxin: y

Trivial name:

3H-​2-​Benzopyran-​7-​carboxylic acid, 4,​6-​dihydro-​8-​hydroxy-​3,​4,​5-​trimethyl-​6-​oxo-​, (3R-​trans)​-; Citrinin (6CI); (-​)​-​Citrinin; 4,​6-​Dihydro-​8-​hydroxy-​3,​4,​5-​trimethyl-​6-​oxo-​3H-​2-​benzopyran-​7-​carboxylic acid; NSC 186

Systematic name:

3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)-

Molecular formulae: 

C13H14O5

 

Molecular weight: 250.3

Chemical abstract number: 518-75-2

Chemical type: Benzopyran

Literature reference:

  • Biochemistry of microorganisms. XLII. The metabolic products of Aspergillus terreus Thom. A new mold metabolic product-​terrein. Raistrick, Harold; Smith, Geo. Biochemical Journal (1935), 29, 606-11.
    Production of citrinin by Aspergillus sp. of the Candidus group. Timonin, M. I.; Rouatt, J. W. Canadian Journal of Public Health (1944), 35, 80-8

References URL: 

Aspergillus Species known to produce this metabolite:

Toxicity:

Initially isolated as a broad-spectrum antibiotic but it is nephrotoxic and has an LD50 of 67 mg/kg body-weight when given subcutaneously or intraperitoneally in rats and 19 mg/kg body-weight when given intravenously to rabbits.

Structure image:  

Citrininweb

Date uploaded: 2005-12-13 00:00:00

Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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