Author:
Vasireddy Teja, Bibhuti Saha Hod, Soumendranath Haldar (IN)
Abstract:
Introduction: Invasive mold infections are a growing problem worldwide with invasive aspergillosis (IA) and invasive mucormycosis (IM) as two of the most common mold infections. Increasing incidence of IA and IM is multifactorial. More widespread adoption of aggressive therapy practices including chemotherapy, transplantation, and intensive care use contributes to greater numbers of infections.
Objectives:To report cases with dual mold infections.
Methods: This study presents a series of 7 cases with dual invasive mold infections in patients with underlying multiple risk factors.
Results: Out of 7 cases maximum age group was between 50-60 years and maximum were females. The major risk factor was T2DM. The majority could be diagnosed via culture and HPE. Majority treated with amphotericin B and posaconazole, among 7;4 recovered well and 3 succumbed to death.
Conclusion:In conclusion, there is an urgent and unmet need for well-designed studies on the “net state of immunosuppression” and environmental exposures as risk factors for mixed mold infections. Non-invasive fungal diagnostics, including serial testing by biomarkers and development of new assays, and the efficacy, safety, and cost-effectiveness of antimould prophylaxis in potentially susceptible hosts with characteristics other than transplant or neutropenia. Such clinical-translational research may help decrease morbidity and mortality from invasive mold infections.
Abstract Number: 81
Conference Year: 2024
Conference abstracts, posters & presentations
-
Title
Author
Year
Number
Poster
-
v
Teclegiorgis Gebremariam [MS]1, Yiyou Gu [PhD]1, Sondus Alkhazraji [PhD]1, Jousha Quran1, Laura K. Najvar [BS]2, Nathan P. Wiederhold [PharmD]2, Thomas F. Patterson [MD]2, Scott G. Filler [MD]1,3, David A. Angulo (MD)4, Ashraf S. Ibrahim [PhD]1,3*,
2024
91
n/a
-
v
Ruta Petraitiene (US)
2024
90
n/a
-
v
Fabio Palmieri (CH), Junier Pilar
2024
89
n/a
-
v
Evelyne Côté (CA)
2024
88
n/a
-
v
Eliane Vanhoffelen (BE)
2024
87
n/a
-
v
Teclegiorgis Gebremariam, Yiyou Gu, Eman Youssef, Sondus Alkhazraji, Joshua Quran, Nathan P. Wiederhold, Ashraf S. Ibrahim
2024
86
n/a
-
v
Thomas Orasch (DE)
2024
85
n/a
-
v
Julien Alex, Katherine González, Gauri Gangapurwala, Antje Vollrath, Zoltán Cseresnyés, Christine Weber, Justyna A. Czaplewska, Stephanie Hoeppener, Carl-Magnus Svensson, Thomas Orasch, Thorsten Heinekamp, Carlos Guerrero-Sánchez, Marc Thilo Figge, Ulrich S. Schubert, Axel A. Brakhage
2024
84
n/a
-
v
Vasireddy Teja, Bibhuti Saha Hod, Soumendranath Haldar (IN)
2024
83
n/a
-
v
Vasireddy Teja, Bibhuti Saha Hod, Soumendranath Haldar (IN)
2024
82
n/a