Acute invasive pulmonary aspergillosis with positive Aspergillus blood culture

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This man with non-Hodgkins lymphoma developed acute invasive pulmonary aspergillosis after chemotherapy, splenectomy, abdominal radiotherapy and corticosteroid therapy. His blood culture was positive for A. fumigatus, as was a sputum culture three weeks later. He improved with conventional amphotericin B, but radiologically was stable until the addition of flucytosine. He recovered completely.

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Case history