Acute invasive sinus aspergillosis following cord transplant for AML

Submitted by: Michael on: 15 April 2013

Case number: 33

Summary:

This 19-year-old black male post allogeneic cord transplant for acute myelogenous leukemia-M4 (AML), developed epistaxis and fever and sinus infiltrates consistent with invasive sinus aspergillosis; received micafungin for 77 days in combination with AmBisome after failing a total of 54 day period on AmBisome therapy, including 21 days of combination therapy with AmBisome and caspofungin; the patient achieved a partial response.

Species (if applicable): Aspergillus flavus

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Choose aspergillosis groupingAcute invasive pulmonary aspergillosisAllergic aspergillosisAspergillomaChronic cavitary pulmonary aspergillosisOther invasive diseaseOther types of aspergillosisPaediatric AspergillosisPleural AspergillosisPrimary pulmonary aspergillosisSevere Asthma with Fungal SensitisationSinus aspergillosis in non-immunocompromisedSubacute invasive (chronic necrotizing) pulmonary aspergillosis