Submitted by Aspergillus Administrator on 12 May 2010
People taking antacids (or who have other absorbtion problems) and the antifungal itraconazole have long been advised to take a cola drink with their antifungal in order to aid its uptake into the bloodstream. Other acidic drinks have also been used, most notably acidic fruit juice which has proven to have problems of its own, sometimes improving uptake but decreasing breakdown of the drug in the liver (overall effect can be to over-increase the levels of itraconazol in the blood) and sometimes to actually block uptake
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