Aspergillus Genomes - Aspergillus and Aspergillosis

Showing 10 posts of 693 posts found.

Title

Date

Evidence of unique genetic diversity in Aspergillus fumigatus isolates from Cameroon.

9 July 2018
Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus

10 January 2018
A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates

10 January 2018
The Influence of Genetic Stability on Aspergillus fumigatus Virulence and Azole Resistance

29 December 2017
Global gene expression reveals stress-responsive genes in Aspergillus fumigatus mycelia

14 December 2017
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

27 March 2017
Global Population Genetic Analysis of Aspergillus fumigatus.

13 March 2017
Functional analysis of the gene controlling hydroxylation of festuclavine in the ergot alkaloid pathway of Neosartorya fumigata.

14 March 2016
Genotypic discrimination of Aspergillus fumigatus strain from related species within section fumigati.

21 October 2016
Host response to fungal infections – how immunology and host genetics could help to identify and treat patients at risk.

30 September 2016

CADRE Genomes and ASPGD are both now obsolete and deactivated. For genomic information please use the resources listed below.

JGI (www.jgi.doe.gov):

Also see the JGI Mycocosm for information on the Genomic Encyclopedia of Fungi. This project aims to explore the features of fungal genomes that impact mycorrhyzal symbiosis, plant pathogenicity and biocontrol, as well as lignocellulose degradation, sugar fermentation and other industrial applications.

GenBank (www.ncbi.nlm.nih.gov):

The GenBank database (produced by the National Center for Biotechnology Information, a part of the US National Institutes of Health) holds information on:

• 210 assembled genomes
• >199,000 genes
• >1,000,000 protein sequences

Click here for a full listing

NITE (National Institute of Technology and Evaluation) Biological Research Centre, Japan:

Aspergillus oryzae is mainly known for being used by the food industry in the East for many hundreds of years. The species is employed in the production of soy sauce, koji and sake (among other items) but can also occasionally be a human pathogen.

NITE has performed microbial genome analysis to produce a full manually annotated genome of A. oryzae:

The 37-megabase (Mb) genome of A. oryzae contains 12,074 genes and is expanded by 7-9 Mb in comparison with the genomes of Aspergillus nidulans and Aspergillus fumigatus. Comparison of the three Aspergillus species revealed the presence of syntenic blocks and A. oryzae-specific blocks (lacking synteny with A. nidulans and A. fumigatus) in a mosaic manner throughout the genome of A. oryzae. The blocks of A. oryzae-specific sequence are enriched for genes involved in metabolism, particularly those for the synthesis of secondary metabolites. Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation.

Click here for more information

Other Search Tools and Resources:

1000 Fungal Genomes Project contains several Aspergillus genomes not present elsewhere

Aspergillus Genetic Information
Aspergillus home page at the Fungal Genetics Stock Center (FGSC)

Aspergillus nidulans Gene Knock-Out Cassettes from the FGSC
The Fungal Genetic Stock Center (FGSC) can provide DNA suitable for transformation or amplification. A spreadsheet listing the A. nidulans cassettes and primers is available for download, and more information is available on the FGSC web site.

The Aspergillus nidulans Linkage Map
John Clutterbuck’s web site at the University of Glasgow, with A. nidulans linkage data and maps, gene lists and functional information, strain information, and references

Aspergillus Comparative Database
Genome sequence, annotation, and tools at the Broad Institute: includes A. fumigatus, A. flavus, A. nidulans, A. niger, A. terreus, A. oryzae, N. fischeri, A. clavatus.

Aspergillus fumigatus Genome Project at the Sanger Institute
Sequencing and annotation of the A. fumigatus genome, performed at the Sanger Institute

J. Craig Venter Institute (JCVI) Aspergillus genome research

Title

Date

JGI (www.jgi.doe.gov):

GenBank (www.ncbi.nlm.nih.gov):

NITE (National Institute of Technology and Evaluation) Biological Research Centre, Japan:

Other Search Tools and Resources: