Three new dioxopiperazine metabolites from a marine-derived fungus Aspergillus fumigatus Fres

Author:

Zhao WY, Zhu TJ, Fan GT, Liu HB, Fang YC, Gu QQ, Zhu WM

Date: 11 June 2010

Abstract:

Three new dioxopiperazine metabolites (1-3), together with two known compounds, N-acetyltyramine (4) and cyclo-(Ala-Val) (5), were isolated from a marine-derived fungus Aspergillus fumigatus Fres. Their structures were established by spectroscopic methods. Their cytotoxic activities against the K562 cell line were preliminarily evaluated by the sulphorhodamine B (SRB) method.

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