Pulmonary Coinfection of Pneumocystis jirovecii and Aspergillus Species
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Date: 13 January 2025
Abstract:
In this multicenter study of 387 patients who were immunocompromised, 4.5% with invasive pulmonary aspergillosis also had Pneumocystis jirovecii pneumonia. Predictors of coinfection included elevated β-D-glucan and prolonged corticosteroid use. Coinfection correlated with reduced 30-day survival (22% vs 57%), suggesting that early identification and prophylaxis may improve outcomes.
Keywords: PCP-IPA coinfection; Pneumocystis jirovecii; aspergillosis; immunocompromised patients; invasive pulmonary aspergillosis.
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