Pulmonary aspergillosis in the context of AML

Case number: 

26

Summary: 

This 75 year old white male with a history of newly-diagnosed acute myelogenic leukaemia (AML) developed probable pulmonary aspergillosis. He was diagnosed based on chest CT (consolidation and nodules) and consecutive positive ELISAs. He was refractory to Abelcet (with progression of disease) and intolerant of Amphotericin B (increase of creatinine >2.5). He was treated with caspofungin for 6 days, but he finally died with deterioration of his lung disease and acute neurological symptoms, due possibly to dissemination of fungal infection. No autopsy was performed to define the diagnosis and extent of the disease.

Computed content type (Case History): 

Case history