Malformin A

Toxin: 

y

Trivial name: 

Malformin A (7CI,​8CI); 15,​16-​Dithia-​2,​5,​8,​11,​19-​pentaazabicyclo[11.4​.2]​nonadecane, cyclic peptide deriv.; Malformin A1

Systematic name: 

Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1®2)-disulfide<br />&#13; Malformin A&#13;

Molecular formulae: 

C23H39N5O5S2

Molecular weight: 

529.72

Chem abstract number: 

3022-92-2

Literature reference: 

Chemical studies on malformin. I. Malformin A. Marumo, Shingo; Curtis, Roy W. Phytochemistry (Elsevier) (1962), 1, 245-57.&#13; Malformins from Aspergillus ficuum, A. awamori, and A. phoenicis. Iriuchijima, Shinobu; Curtis, Roy W. Phytochemistry (Elsevier) (1969), 8(8), 1397-9.&#13; Asperpyrone D and other metabolites of the plant-​associated fungal strain Aspergillus tubingensis. Zhan, Jixun; Gunaherath, G. M. Kamal B.; Wijeratne, E. M. Kithsiri; Gunatilaka, A. A. Leslie. Phytochemistry (Elsevier) (2007), 68(3), 368-372.&#13; &#13;

Toxicity: 

Antibiotic. &#13; mouse LD50 intraperitoneal 3100ug/kg (3.1mg/kg) EFFECTS: GASTROINTESTINAL: OTHER CHANGES. LIVER: OTHER CHANGES. &#13; KIDNEY, URETER, AND BLADDER: OTHER CHANGES Agricultural and Biological Chemistry. Vol. 39, Pg. 1325, 1975.

Structure image: 

Species known to produce this metabolite: 

3d image file .c3d (requires Chem3d http://www.cambridgesoft.com/Ensemble_for_Chemistry/ChemBio3D/): 

jmol file (.mol) requires Java to run (http://www.java.com/en/download/help/enable_panel.xml): 


Date uploaded: 

2008-07-07 16:58:01