DIFFICULT CASES OF ALLERGIC AND CHRONIC PULMONARY ASPERGILLOSIS

Eavan Muldoon, Chris Kosmidis

Abstract: 

Chronic pulmonary aspergillosis (CPA) is a progressive, debilitating infection associated with substantial 
morbidity and mortality. Diagnosis may be missed because of the non-specific symptoms and poor sensitivity 
of culture. Oral antifungals offer an improvement in quality-of-life parameters, but prolonged treatment is 
often required as recurrences are common. Prolonged antifungal treatment is associated with high cost and 
an extensive side effect profile frequently leading to discontinuation. In addition, resistance developing 
during treatment is a common problem that limits our therapeutic options. Challenging CPA cases will be 
presented, and the step-by-step management will be discussed, focusing on the difficulties in recognition, 
diagnosis and treatment.

2016

Full conference title: 

7th Advances Against Aspergillosis