To know the knowledege, attitude and practice about aspergillosis among healthcare professional in developing country.
142 health care professional, nursing and pharmacist was asked to fill the standard questionaires about aspergillosis knowledge, attitude and practice in 2 district western part of Nepal.
72% of medical professional had the knowledge about the aspergillosis but 31% thought that it is rare case that can not be diagnose correctly in resource poor setting. 13% of nursing personel had not correct knowledge about it. 69% Pharmacist donot have the advance medicine against aspergillosis and the selling the antifungal drugs without any prescription is on practice. Prevention knowledge from aspergillosis is poor (48%).
Developing country in south asia like India, Nepal having with a high burden of HIV and endemic fungal infection. H. capsulatum and C. neoformans alone are the major causes of HIV related deaths. The main fungal infections in the country are respiratory, gastrointestinal and dermatologic. Among respiratory fungal infections the most prevalent is H. capsulatum, however other endemic fungi infections have been reported.
As sub-optimum hospital care practice, hospital renovation work in the vicinity of immunocompromised patients, overuse or misuse of steroids and broad-spectrum antibiotics, use of contaminated infusion sets/fluid, packed food and increase in intravenous drug abusers are the predisposing factors for the infection of aspergillosis. Clinicians are aware of good outcome after use of newer drugs like voriconazole/liposomal amphotericin B/caspofungin, but they are forced to use amphotericin B deoxycholate or itraconazole in public-sector hospitals due to economic reasons. Public Health programs are important to spread the knowledge about it.